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Generally speaking, it ranks among the most prevalent oral diseases, obviously impacting individual oral health and quality of life ( Oxidative stress refers to the phenomenon where excessive production of oxygen free radicals and other oxidants in the cellular and extracellular environment overwhelms the bodys antioxidant defense systems, which leads to cellular functional damage ( In the management of periodontitis, antioxidant therapy has appeared as a potential treatment strategy garnering wide attention

Given the heterogeneity of WD, selecting endpoints to adequately capture symptoms and impacts across all patients is challenging

Hassani A, Hussain SA, Abdullah N, Kmaruddin S (2018) Review on micro-encapsulation with Chitosan for pharmaceuticals applications

The results reported various ranges of blood-to-plasma ratios, some of which significantly differ from those found in the literature

doi: 10.3390/nu12041185 160 WangJJiHWangSLiuHZhangWZhangDet al